The Possible Effects of Green Coffee Bean Extract on Progression of Experimental Diabetes in Different Organs; A Review Article

Abdel Mohsen, Doaa; Akabawy, Ahmed M. A; Abdemoneim, Ahmed; Amin, Hatem K.

doi:10.21608/aprh.2021.77827.1133

The Possible Effects of Green Coffee Bean Extract on Progression of Experimental Diabetes in Different Organs; A Review Article

Document Type : Review Article

Authors

¹ Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Cairo, Egypt.

² Department of Zoology and Entomology, Faculty of Science, Helwan University, Cairo, Egypt.

10.21608/aprh.2021.77827.1133

Abstract

Green coffee bean water extract consumption has been stated to have a contrary association with type 2 diabetes and metabolic syndrome. Chlorogenic acid (CGA), an important biologically active dietary polyphenol, is produced by certain plant species and is a major component of coffee. Reduction in the risk of a variety of diseases following CGA consumption has been mentioned in recent basic and clinical research studies. This systematic review discusses in vivo animal and human studies of the physiological and biochemical effects of CGA on biomarkers of diabetic complication and the possible alterations produced by the administration of different doses of green coffee on biomarkers related to renal, testicular, and neurological antioxidant systems.

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