Korany, E., Soliman, H., Abd El Gawwad, M., El Naggar, N., Ibrahim, H. (2022). Phytochemical Screening and Antimicrobial activity of Physalis peruviana L. calyces. Journal of Advanced Pharmacy Research, 6(1), 1-5. doi: 10.21608/aprh.2021.104236.1144
Eslam Korany; Hesham Soliman; Maryam Abd El Gawwad; Nora El Naggar; Haitham Ibrahim. "Phytochemical Screening and Antimicrobial activity of Physalis peruviana L. calyces". Journal of Advanced Pharmacy Research, 6, 1, 2022, 1-5. doi: 10.21608/aprh.2021.104236.1144
Korany, E., Soliman, H., Abd El Gawwad, M., El Naggar, N., Ibrahim, H. (2022). 'Phytochemical Screening and Antimicrobial activity of Physalis peruviana L. calyces', Journal of Advanced Pharmacy Research, 6(1), pp. 1-5. doi: 10.21608/aprh.2021.104236.1144
Korany, E., Soliman, H., Abd El Gawwad, M., El Naggar, N., Ibrahim, H. Phytochemical Screening and Antimicrobial activity of Physalis peruviana L. calyces. Journal of Advanced Pharmacy Research, 2022; 6(1): 1-5. doi: 10.21608/aprh.2021.104236.1144
Phytochemical Screening and Antimicrobial activity of Physalis peruviana L. calyces
1Pharmacognosy Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, 11795
2Microbiology Department, Faculty of Pharmacy, Helwan University, Ain Helwan, Cairo, 11795
Abstract
Background: The Goldenberry (Physalis peruviana L.) calyces are rich in phytochemical compounds which have promising biological activity. Objective: In the present study, a preliminary phytochemical screening was performed to explore the nature of calyces. The total methanolic extract and n-butanol fraction of P. peruviana calyces were investigated in terms of their antimicrobial activity. Method: Methanol extract and n-butanol fraction were tested for their anti-microbial activity against Gram-positive, Gram-negative bacteria, and Candida albicans using the disc diffusion method. Results: Phytochemical screening showed that calyces are rich in saponins, flavonoids, Steroids and/or triterpenes, Carbohydrates and/or glycosides; while Alkaloids and/or nitrogenous base, tannins, Anthraquinones were absent. The n-butanol fraction showed inhibition zones (16 ± 0.16 mm) for B. subtilis and (10 ± 0.17 mm) for S. aureus, while the methanolic extract showed inhibition zones of (13 ± 0.21 mm) and (8 ± 0.18 mm) for B. subtilis and S. aureus, respectively. On the other hand, no inhibition zones were detected for Gram-negative bacteria or C. albicansConclusion: The total methanolic extract and n-butanol fraction displayed strong antibacterial activity against B. subtilisthan S.aureus, while both of them didn’t show activity against Gram-negative strains or C. albicans
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