Mahgoub, S., Abosalem, H., Mahmoud, D., Abdel Mohsen, D., Abd-eltwab, Z. (2022). Crosstalk between Maternal Life and Fetal Epigenome; A Review Article. Journal of Advanced Pharmacy Research, 6(4), 181-191. doi: 10.21608/aprh.2022.144865.1181
Shahenda Mahgoub; Hadeer Abosalem; Dina Mahmoud; Doaa Abdel Mohsen; Zeinab Abd-eltwab. "Crosstalk between Maternal Life and Fetal Epigenome; A Review Article". Journal of Advanced Pharmacy Research, 6, 4, 2022, 181-191. doi: 10.21608/aprh.2022.144865.1181
Mahgoub, S., Abosalem, H., Mahmoud, D., Abdel Mohsen, D., Abd-eltwab, Z. (2022). 'Crosstalk between Maternal Life and Fetal Epigenome; A Review Article', Journal of Advanced Pharmacy Research, 6(4), pp. 181-191. doi: 10.21608/aprh.2022.144865.1181
Mahgoub, S., Abosalem, H., Mahmoud, D., Abdel Mohsen, D., Abd-eltwab, Z. Crosstalk between Maternal Life and Fetal Epigenome; A Review Article. Journal of Advanced Pharmacy Research, 2022; 6(4): 181-191. doi: 10.21608/aprh.2022.144865.1181
Crosstalk between Maternal Life and Fetal Epigenome; A Review Article
1Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo,11795, Egypt.
2Egyptian drug authority (EDA), Giza, 12654, Egypt.
Abstract
Background: It is important to say that maternal lifestyle during gestation could affect embryonic development and health consequences. Objectives: Many endogenous and exogenous factors affect the epigenetics of the germ cells during their division and subsequently affect the embryogenesis. Methods: This systematic review outline various studies that link the different environmental factors and modification in the fetal epigenome. Conclusion: Aberrant fetal epigenome modification subsequently affects the healthy embryonic growth and their contribution to the phenotypic changes and chronic disease development later in life.
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