Crosstalk between Maternal Life and Fetal Epigenome; A Review Article

Document Type : Review Article

Authors

1 Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo,11795, Egypt.

2 Egyptian drug authority (EDA), Giza, 12654, Egypt.

Abstract

Background: It is important to say that maternal lifestyle during gestation could affect embryonic development and health consequences. Objectives: Many endogenous and exogenous factors affect the epigenetics of the germ cells during their division and subsequently affect the embryogenesis. Methods: This systematic review outline various studies that link the different environmental factors and modification in the fetal epigenome. Conclusion: Aberrant fetal epigenome modification subsequently affects the healthy embryonic growth and their contribution to the phenotypic changes and chronic disease development later in life.

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Journal of Advanced Pharmacy Research
Volume 6, Issue 4
October 2022
Pages 181-191

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